What Are The Advantages Of LC/MS Nitrogen Generator?

The nitrogen generator produces a continuous flow of high-purity nitrogen at the selected pressure. LC/MS nitrogen generator can analyze chemical molecule movement and characteristics.

Advantage of LC/MS nitrogen generator

Small footprint- Easy to meet footprint requirement

Extensive Operation- Custom-designed skids

Remote Operation- Require minimal attention and fully automated systems

Simple Solution- Require Minimal Maintenance

No Chemicals- Environmentally Friendly

Minimal Losses- Low HC losses

Uses of nitrogen in Mass Spec

To keep sample solvents from getting to necessary LC/MS components, nitrogen is typically used in the removal process. Before solvents may affect the quality of the assay and spectroscopic detectors, nitrogen will destroy them. How nitrogen is employed within an LC/MS are:

·         Electrospray Ionization Detectors

·         Atmospheric Pressure Ionization Detectors

·         Curtain Gas

Reasons to use nitrogen generator for LC/MS

One of the best choices for analytical processes is the decision to incorporate an onsite nitrogen generator for operators using LC/MS equipment. The nitrogen generator confers various benefits such as reduced cost of production, ease of use and convenience, increased operational safety, and reduction in overall energy costs.

Increased Operational Safety

The risk involved with handling and storing nitrogen cylinders is removed by using an on-site nitrogen generator. When nitrogen is created on-site, accidental leaks resulting from defective storage containers or gas tubing can be efficiently prevented because just the necessary amount is produced. Having LC/MS nitrogen generator safety on-site protects workers from the negative consequences of storing nitrogen cylinders, which improves the entire working environment.

·         Easy To Use

The simplicity of energizing the nitrogen needed for LC/MS systems only when necessary is a definite benefit. Transporting and using storage cylinders is no longer necessary thanks to nitrogen generators. Also, on-site generation reduces the need for valuable floor space that would have been set aside for the storage of large gas cylinders.

·         Cheaper operational cost

An on-site nitrogen generator has operating costs that are much lower than those of provided nitrogen cylinders after the first installation. Nitrogen cylinder replacement and recalibration increase equipment downtime in addition to delivery expenses, ongoing maintenance costs, and safety checks—all of which are unaffected by the usage of nitrogen generators.

·         Capillary columns

Capillary columns are gas chromatography columns with a stationary phase-coated inner surface rather than packed into the cavity. It is used to analyze samples for individual chemical compounds they contain. As compared to the packed column the capillary GC column has more efficient separation of the sample.

How to choose Capillary columns?

A common kind of capillary column for gas chromatography has a coating of the stationary phase on the interior of the column. Because they require less sample for the chromatography process, these columns are generally favored over the packed variants. When it comes to the column's dimensions, it has a diameter that is only a few tenths of a millimeter in size.

Your choice should be based on the general considerations:

·         Sample Size

There is no longer a need for big sample injections because modern detectors are highly sensitive. Capillary columns should be the first option in such circumstances. Nonetheless, packed columns can be taken into consideration if the detector sensitivity is poor because they have higher sample load capacities.

·         Ruggedness

Although metallic columns are tough and can withstand any handling, caution should be taken to avoid dropping them as this could upset the packing inside and reduce separation power.

·         Sample Polarity

Most packed columns are composed of glass or stainless steel. Glass columns are more suited for polar compound separations than stainless steel columns and are typically beneficial for non-polar compound separations.

GC Consumables

To separate and identify components in a volatile sample Gas chromatography is an analytical technique. It is used on compounds that have passed boiling point at room temperature and have a molecular weight of less than 1250 Da. GC consumables provide you with the best possible separation. Quadrexcorp understands your chromatography analysis does not end with the selection of the GC column.